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Life Extension Vitamin B12, 500 mcg, 100 Lozenges

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Life Extension Vitamin B12 (cyanocobalamin) lozenges supports brain and nervous system function, blood, DNA & anemia. Older adults, gastrointestinal surgery patients, vegetarians, and vegans typically have an absorption issue or do not get enough B12.

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Description

Vitamin B12 is present in foods of animal origin, including dairy products and eggs. Thus, vegetarians are more susceptible to a dietary deficiency of this important nutrient.224 Likewise, vitamin B12 serum concentrations are reported to be significantly lower in elderly population groups compared to younger groups.225-228 It is estimated that 10% to 30% of individuals over the age of 50 have low stomach acid secretion229,230 which results in decreased bioavailability of vitamin B12 from food. To overcome food-bound vitamin B12 malabsorption problems, the Institute of Medicine recommends that vitamin B12-fortified foods (such as fortified ready-to-eat breakfast cereals) or supplements containing vitamin B12 be used to meet much of the requirement.231 Vitamin B12, or cobalamin, works synergistically with vitamin B6 and folate to regenerate (methylate) the amino acid methionine, which helps to maintain already healthy homocysteine levels within normal range, which is important for heart health.232-235

Cyanocobalamin is a synthetic and inexpensive form of vitamin B12 that is converted in the body to its bioactive forms, methylcobalamin and cobamamide. It plays a key role in brain and nervous system function2 and the cells involved in the creation of blood.1,2 Vitamin B12 is involved in the metabolism of every cell in the body including the creation and regulation of DNA, synthesizing fatty acids, and the production of energy. It may also help prevent a type of anemia that makes people tired and weak.1 Since the human body cannot produce Vitamin B12, supplementation is required.2

People over the age of 50, vegetarians/vegans, patients with digestive issues such as celiac or Chrohn’s disease, and those who have had weight loss or other gastrointestinal surgeries may have a reduced ability to absorb enough vitamin B12 or just don’t get enough. A few examples of B12 deficiency are anemia, weakness, numbness or tingling in the extremities, and loss of balance.3

 

Supplement Facts

Serving Size: 1 lozenge

Servings Per Container: 100

Amount Per Serving

Vitamin B12 (as cyanocobalamin)

500 mcg

Other Ingredients: mannitol, sorbitol, microcrystalline cellulose, vegetable stearate, croscarmellose sodium, natural strawberry flavor.

Dosage and Use:

  • Take one lozenge one to four times daily with or without food, or as recommended by a healthcare practitioner.
  • Place lozenge in mouth and allow to dissolve, then swallow.

Warnings:

  • If pregnant, nursing, or taking medication, consult your physician before taking this product
  • Keep out of reach of children
  • Do not exceed recommended dose

References:

1. ODS Dietary Supplement Fact Sheet: Vitamin B12
2. Wikipedia: Vitamin B12
3. MedlinePlus: Vitamin B12
224. Exp Biol Med (Maywood). 2007 Nov;232(10):1266-74.
225. Am J Clin Nutr. 1999;70:904-910.
226. Am J Clin Nutr. 1994;60:2-11.
227. Am J Clin Nutr. 1994;60:12-14.
228. Prev Med. 2004 Dec;39(6):1256-66.
229. JAMA. 1997 Aug 27;278(8):659-62.
230. J Am Geriatr Soc. 1986 Nov;34(11):800-6.
231. Epidemiology. 2007 May;18(3):367-8.
232. Handb Exp Pharmacol. 2005;(170):325-38.
233. Altern Med Rev. 2003 Feb;8(1):7-19.
234. Lancet. 2002 Jan 19;359(9302):227-8.
235. Asia Pac J Clin Nutr. 2007;16(1):103-9.

 

* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.

 

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