Metagenics Axis Endo, Endocrine Support Multivitamin, Mango Flavored, 19.75 oz. Powder

Our Price: $84.44

People are finally beginning to realize that they can get a lot more out of their daily multivitamin. Metagenics Axis Endo contains all the vitamin and mineral content one would expect from a daily multiple of quality, with added phytonutrients for endocrine system support. For those struggling with hormonal balance, this may be the multivitamin for you!

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SKU: M50857 Category:


  • A quality multivitamin powder specifically designed to support the endocrine system.
  • Standard nutrient content includes vitamin A, vitamin C, vitamin D, magnesium, calcium, zinc, and more.
  • Advanced phytonutrient content includes curcumin, silymarin, rosemary extract, dried melon extract, and mixed carotenoids.
  • Provides a wide range of antioxidant and anti-inflammatory support.
  • Can be useful for women’s health and men’s health issues.
  • Tasty mango flavor.

The Next Level of Multivitamin Support

Millions of people all around the world rely on a daily multivitamin to round out their dietary intake. This is a viable health solution, particularly for those who struggle to regularly incorporate whole foods into their diet. However, it also begs the question: why just stop at the basics?

Everyone’s body is different. We struggle with different health complications depending upon numerous specific factors like our environment, lifestyle choices, and even genetic makeup. So why should all our multivitamins have relatively the same ingredients?

Finally, the nutraceutical industry has taken notice of this issue and now countless multivitamins are being manufactured to serve people with specific health concerns, while also rounding out their general dietary intake. Axis Endo from Metagenics is one such multivitamin.

Axis Endo contains standard dosages of every vitamin and mineral one would expect to find in a quality multiple. This includes vitamin A, vitamin C, vitamin D, magnesium, calcium, zinc, and more! But what sets this multi apart is its phytonutrient content which has been carefully selected and dosed to provide nutritional support for those who are struggling with their endocrine system.

Phytonutrients and the Endocrine System

While the majority of studies on the effects of various phytonutrients on the endocrine system have been done primarily with animal models, there seems to be enough evidence to suggest that they could have a significant impact on humans as well.

Lobes of Thyroid Gland

Curcumin, for example, has been rigorously studied for its anti-inflammatory support properties in humans. It has been suggested that by fighting inflammation which otherwise negatively impacts the function of endocrine receptors, curcumin may provide meaningful support for the healthy function of the endocrine system as a whole.1

Meanwhile, the silymarin contained in milk thistle may be a useful facet in the transportation of thyroid hormones across cell membranes.2

This only scratches the surface of the deep scientific literature which links the various effects of phytonutrients in the body to the overall function of the endocrine system. In addition to the ingredients listed above, Axis Endo also contains rosemary extract, dried melon extract, and mixed carotenoids; with the potent antioxidant n-acetyl-cysteine (NAC) thrown in for additional antioxidant protection of endocrine receptors and other important cells.


Note: This product is non-GMO and gluten-free.

Storage: Keep closed in a cool, dry place.

Caution: Consult your healthcare practitioner prior to use if taking medications or other nutritional supplements.


  • If pregnant, nursing, or undergoing treatment for a medical condition, consult your physician before taking this product
  • Keep out of reach of children
  • Do not exceed recommended dose

* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.

Supplement Facts

Serving Size: 2 Scoops

Servings Per Container: 14

Amount Per Serving



Calories From Fat


Total Fat

5 g

Total Carbohydrate

15 g

Dietary Fiber

7 g


2 g


13 g

Vitamin A (as mixed carotenoids)

2500 IU

Vitamin C (as ascorbic acid)

60 mg

Vitamin D (as cholecalciferol)

1000 IU

Vitamin E (as d-alpha tocopheryl succinate)

300 IU

Vitamin K (as menaquinone and phylloquinone)

90 mcg

Thiamin (as thiamin HCl)

0.75 mg


1 mg

Niacin (as niacinamide)

10 mg

Vitamin B6 (as pyridoxine HCl)

50 mg

Folate (as calcium L-5-methyltetrahydrofolate)

400 mcg

Vitamin B12 (as methylcobalamin)

300 mcg


150 mcg

Pantothenic Acid (as calcium D-pantothenate)

5 mg

Calcium (as calcium D-glucarate and calcium citrate)

500 mg

Iron (as ferrous fumarate)

13.5 mg


350 mg

Iodine (as potassium iodide)

100 mcg

Magnesium (as magnesium citrate)

200 mcg

Zinc (as zinc citrate)

12 mg

Manganese (as manganese sulfate)

1 mg

Chromium (as chromium picolinate)

100 mcg


120 mg

Potassium (as dipotassium phosphate and potassium iodide)

400 mg

Flaxseed Hull (containing lignans)

1.84 g

Calcium D-Glucarate

1.5 g

Milk Thistle (Silybum marianum)Seed Extract providing 140 mg silymarin (containing silybin, isosilybin, silydianin, silychristin)

280 mg

Proprietary Mix of Curcumin from Curcuma longa L. rhizome extract standardized to 40% (40 mg) curcuminoids] and Fenugreek Galactomannans (from Trigonella foenum-graecum seed extract)

100 mg


100 mg

Rosemary (Rosmarinus officinalis)Leaf Extract (standardized to 7.6% min sum of carnosol+carnosic acid)

100 mg

Dried Melon (Cucumis melo L.)Pulp Juice Concentrate [standardized to 140 IU superoxide dismutase (SOD)]

10.2 mg

Mixed Carotenoids (including beta-carotene, alpha-carotene, cryptoxanthin, zeaxanthin, and lutein)

1.5 mg

Other Ingredients: Pea protein isolate, Rice protein concentrate, Apple fiber, Partially hydrolyzed guar gum, High oleic sunflower oil, Medium-chain triglycerides, Natural flavors, Tapioca flour, Silica, Mono and diglycerides, Luo Han Guo fruit (monk fruit) extract, Hydrogenated palm oil

Dosage & Use

  • Blend or shake 2 level scoops (40 grams) of Axis Endo into 8 fluid ounces of water, juice, or soy, almond, rice, coconut or organic cow’s milk once or twice daily as directed by your healthcare practitioner.
  • For highly sensitive individuals, consider reducing consumption to 1/2 to 1 scoop with 4-5 ounces of chilled water or recommended fluid twice daily during the first 3-4 days before starting a full daily dose.


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1. Curcumin Study
2. Milk Thistle Study