Metagenics Insinase, 90 Vegetarian Tablets

Our Price: $80.00

Insinase is one of the Metagenics vitamins that contains selective kinase response modulators, RIAA and acacia, designed to support healthy cellular insulin function. Designed to aid in kinase signaling (within cells) in favor of healthy insulin function and blood sugar transport.

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  • Ground-breaking preliminary research suggests that SKRMs supports kinase signals in favor of good health
  • Balanced kinase signaling helps to maintain healthy blood sugar and triglyceride regulation
  • Developed through the ExpresSyn Process
  • In vitro testing of the active ingredients has demonstrated support of IL-6 cytokines at a natural level+

Studies on the Effects of Acacia

Insinase features selective kinase response modulators (SKRMs) – RIAA and acacia. In a randomized, double-blind, placebo controlled trial of acacia, there was significant support of natural plasma glucose and insulin levels. There were no adverse side effects. This suggests potential for acacia to aid in glucose homeostasis in patients with impaired glucose tolerance.1

Frequently Asked Questions

Q. How does Insinase® compare to other products or approaches?

A. As a nutraceutical, this product is formulated to complement dietary measures to promote healthy insulin function. It provides a novel blend of natural selective kinase response modulators (SKRMs) that offer scientifically evaluated cellular support for healthy insulin function. This product contains only natural ingredients and provides a safer course for long-term healthy insulin function support. It has been clinically reviewed at the FMRC.*

Q. How does Insinase® work?

A. It provides a unique combination of ingredients to support healthy insulin function. Cellular studies showed that the RIAA and acacia in Insinase inhibit IL-6 cytokines that can influence insulin function. These ingredients also act as selective kinase response modulators (SKRMs) in fat-storing cells involved in glucose and insulin activities. Balanced kinase (specialized enzyme) signaling helps to maintain healthy blood insulin function, and SKRMs can enhance “healthy” signals from a targeted dietary plan, such as a low-glycemic-load diet.*

Q. How long is Insinase® typically recommended?

A. This formula was designed for insulin function support on a daily basis where appropriate. Your health care professional may recommend regular follow-up visits to re-evaluate markers of blood sugar health. Individual results may vary. For best results, follow your health care professional’s guidelines.*

Q. Who would benefit from Insinase®?

A. Health care professionals recommend this product to promote healthy blood sugar levels already in the normal range, specifically support for healthy insulin function. It provides a complement to dietary signals from a healthy eating plan for added support.*

Q. Why is Insinase® safe?

A. It contains a blend of natural ingredients with an excellent safety profile. Plus, Metagenics’ manufacturing facility has 3 certifications for good manufacturing practices to ensure the highest quality. Key active ingredients in this formula were developed through the ExpresSyn Process(r) that sets a new standard in clinical certainty for natural products via demonstrated efficacy, bioavailability, and a high level of predicted safety. Insinase has been clinically reviewed at the FMRC. (This product is not recommended for those taking anticoagulant medications. MetaGlycemX may be an excellent alternative.)



  • Do not use if pregnant, nursing, or taking anticoagulants.
  • If taking medication, consult your physician before taking this product
  • Keep out of reach of children
  • Do not exceed recommended dose

* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.


Supplement Facts

Serving Size: 3 Tablets

Servings Per Container: 30

Amount Per Serving
A proprietary blend of:

RIAA (Reduced Iso-Alpha Acids)

Acacia Bark

Heartwood Extract, Acacia nilotica

540 mg
Other Ingredients: Microcrystalline cellulose, cellulose, stearic acid (vegetable), croscarmellose sodium, sodium starch glycolate, silica, and coating (hypromellose, medium chain triglycerides , hydroxypropylcellulose, and sodium copper chlorophyllin)
Formulated to Exclude: Wheat, gluten, corn protein, soy, dairy products, nuts, tree nuts, fish, crustacean shellfish, artificial sweeteners, and preservatives. This product is Gluten Free and Vegetarian.

+Based on in vitro and in vivo testing conducted by MetaProteomics, the laboratory research arm of Metagenics. FMRC (Functional Medicine Research CenterSM) is the clinical research arm of Metagenics.

Dosage & Use

  • Take three tablets daily or as directed by your healthcare practitioner.


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1. Effect of acacia polyphenol on glucose homeostasis in subjects with impaired glucose tolerance: A randomized multicenter feeding trial