Description
Lactoferrin is one of the transferrin proteins that transfer iron to the cells and control the level of free iron in the blood and external secretions. It has antimicrobial activity and is part of the innate defense. Though human colostrum (“first milk”) has the highest concentration, followed by human milk, then cow’s milk, lactoferrin is found throughout the human body.37,38
Published studies examining lactoferrin as a supplement and its beneficial effects on immunity have been quite promising.39-43 Lactoferrin helps maintain a proper level of “good” bacteria in the intestinal tract, while controlling the number of “bad” bacteria.44-48 Lactoferrin is also known to have an extremely high affinity to bind to iron.49-51
Lactoferrin is part of the innate immune system, the first line of defense to protect us from infection.1 Because of this, it has antibacterial, antifungal, and antiviral properties.2 It has also been shown to support bone formation.3,4 Lactoferrin looks promising in the support of breast cancer.5
Supplement Facts
Serving Size: 1 capsule Servings Per Container: 60 | |
Amount Per Serving | |
Lactoferrin (from bovine whey) | 300 mg |
Other Ingredients: microcrystalline cellulose, vegetable cellulose (capsule), silica, stearic acid. Contains milk. |
Dosage and Use:
- Take one capsule daily with or without food, or as recommended by a healthcare practitioner.
Warnings:
- If pregnant, nursing, or taking medication, consult your physician before taking this product
- Keep out of reach of children
- Do not exceed recommended dose
References:
1. Paul Grasso. Essentials of Pathology for Toxicologists. CRC Press. Retrieved 30 August 2011. “Our immune system is therefore crucial to our survival. It is currently divided into two categories which are innate (non-specific) immunity and acquired (specific) immunity.”
2. “Lactoferrin: a review”. Veterinarni Medicina 53 (9): 457. 2008.
3. Milk ribonuclease-enriched lactoferrin induces positive effects on bone turnover markers in postmenopausal women.
4. Inflammatory responses improve with milk ribonuclease-enriched lactoferrin supplementation in postmenopausal women.
5. McCormick JJ, Larson LJ, Rich MA (1974). “RNase inhibition of reverse transcriptase activity in human milk”. Nature 251 (5477): 737–40.
6. Wikipedia: Lactoferrin
37. Cell Mol Life Sci. 2005 Nov;62(22):2540-8.
38. Biochimie. 2009 Jan;91(1):30-4.
39. Curr Pharm Des. 2009;15(17):1956-73.
40. Postepy Hig Med Dosw (Online). 2007;61:261-7.
41. Arch Immunol Ther Exp. 1998;46(4):231-40.
42. Adv Exp Med Biol. 1998;443:261-5.
43. J Gastroenterol. 2010 Nov;45(11):1121-8.
44. Am J Gastroenterol. 2007 May;102(5):951-6.
45. Antimicrob Agents Chemother. 2009 Aug;53(8):3308-16
46. Clin Exp Immunol. 2009 Jul;157(1):60-70.
47. J Appl Bacteriol. 1992 Dec;73(6):472-9.
48. Biochim Biophys Acta. 1992 May 22;1121(1-2):130-6.
49. Postepy Hig Med Dosw (Online). 2010 Nov 30;64:604-16.
50. Int J Antimicrob Agents. 2009 Apr;33(4):301.e1-8.
51. Biochimie. 2009 Jan;91(1):11-8.
52. Clin Med Res. 2006 Jun;4(2):106-13.
53. J Vasc Res. 2004 Jul-Aug;41(4):293-304.
54. Dig Dis Sci. 2004 Apr;49(4):579-89.
55. Dig Dis Sci. 2003 Jul;48(7):1324-32.
56. Arch Immunol Ther Exp. 2001;49(4):325-33.
* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.
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