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Life Extension Vitamin B3 Niacin, 500 mg, 100 Capsules

Item Number: 00372 | Be the first to review this product!

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Supplement Overview

Item Catalog Number: 00372
100 Capsules
Also available: 1000 mg
Click to View Supplement Facts

Niacin is the only B vitamin that can be synthesized in the body. It is crucial to the metabolism of glucose, fat, and alcohol. May support cholesterol and triglyceride levels. It is a water soluble vitamin so you need a continuous supply of B3/niacin.1

Many B vitamins are used in the body individually or in combination with enzymes to help release energy from carbohydrates, fat, and protein. Vitamin B coenzymes are crucial to the metabolic pathways that generate the energy needed by every cell in the body. Because they are codependent in their metabolic activities, a deficiency of one B vitamin can affect optimal functioning of organ systems throughout the body.153

Niacin is the only B vitamin that can be synthesized in the liver from the amino acid tryptophan - on average, 1 mg of niacin can be synthesized from the ingestion of 60 mg of tryptophan.188-190 In its coenzyme forms, niacin is crucial to energy transfer reactions, particularly the metabolism of glucose, fat, and alcohol.191,192 Niacin’s beneficial effects on blood lipids is well-documented.193-206

Supplement Facts

Serving Size: 1 capsule

Servings Per Container: 100

Amount Per Serving

Niacin (vitamin B3)

500 mg

Other Ingredients: vegetable cellulose (capsule), ascorbyl palmitate.

Dosage and Use:

  • Take one capsule daily with meals, or as recommended by a healthcare practitioner.

Caution: Temporary flushing, itching, rash, or gastric disturbances may occur. Liver function testing is recommended when niacin is taken in excess of 500 mg daily. Those with gout or liver diseases should avoid taking high doses of niacin.


  • If pregnant, nursing, or taking medication, consult your physician before taking this product
  • Keep out of reach of children
  • Do not exceed recommended dose


1. MedlinePlus: Niacin
153. Ann N Y Acad Sci. 1980;355:80-97. 188. Am J Clin Nutr. 1981 Mar;34(3):423-7.
189. Am J Clin Nutr. 1980 Oct;33(10):2157-67.
190. J Nutr. 1964 Mar;82:395-400.
191. J Am Diet Assoc. 1989 Dec;89(12):1748-52.
192. Nutr Rev. 1975 Oct;33(10):289-97.
193. J Am Geriatr Soc. 1992 Jan;40(1):12-8.
194. Eur J Clin Pharmacol. 1991;40 Suppl 1:S49-S51.
195. JAMA. 1990 Dec 19;264(23):3013-7.
196. Metabolism. 1985 Jul;34(7):642-50.
197. Arch Intern Med. 2002 Jul 22;162(14):1568-76.
198. Arterioscler Thromb Vasc Biol. 2001 Nov;21(11):1783-9.
199. JAMA. 2000 Sep 13;284(10):1263-70.
200. Arch Intern Med. 2000 Apr 24;160(8):1177-84.
201. Am J Cardiol. 2000 May 1;85(9):1100-5.
202. Circulation. 1993 Jul;88(1):20-8.
203. Am J Cardiol. 1998 Sep 15;82(6):737-43.
204. JAMA. 1994 Mar 2;271(9):672-7.
205. Am J Med. 1994 Oct;97(4):323-31.
206. Arch Intern Med. 1994 Jul 25;154(14):1586-95.

* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.

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