Melatonin supplements are capable of providing valuable sleep cycle support and antioxidant activity. While the benefits of melatonin supplementation are undeniable, their bioavailability when orally ingested is thought to be extremely low. Zetpil Melatonin Suppositories dissolve fast but release slow for optimal convenience and vastly superior absorption rates to any oral melatonin supplement.
- 200 mg or 400 mg dose of highest quality melatonin designed for maximum bioavailability.
- Powerful antioxidant and anti-inflammatory properties.
- Supports the development of a healthy sleep schedule.
- No degradation through digestion as with oral supplements.
- Made of an all-natural proprietary suppository base.
- Suppositories can be shipped with ice to ensure preservation of shape and potency.
Sleep Support and Antioxidant Activity
Many people take melatonin supplements to support the development of a healthy sleep schedule. Indeed, melatonin is a naturally produced hormone which plays a significant role in regulating sleep cycles of the human body. It is synthesized at higher rates in darkness as a preparation for sleep and at lower rates in the light to support energy levels throughout the daytime. Those who experience difficulties with maintaining regularity in their sleep cycle, either for health or work related reasons, may find that melatonin supplementation supports them in developing a healthier sleeping schedule.
While many people use melatonin for sleep support, it is less commonly known that it is also among the most powerful antioxidant substances in the human body. This means that its presence in the bloodstream helps to neutralize free radicals and inhibit the development of oxidative stress. It has also been extensively studied for its anti-inflammatory properties.1,2
Bioavailability of Melatonin
While melatonin provides the combined benefits of being a sleep support agent with potent antioxidant properties, there is some question as to whether or not these benefits can be properly harnessed when it is ingested orally. The difficulty with capsule, liquid, or chewable varieties of melatonin supplements is that they must pass through the digestive system where much of their potency is degraded. In fact, the bioavailability of oral melatonin has been scientifically studied and shown to be particularly poor, especially in smaller doses.3
Suppository formulations of melatonin seem to be the most effective means for ensuring the absorption and utilization of this powerful nutrient. By releasing directly into the porous tissues of the lower bowel, suppositories bypass the digestive system entirely and arrive in the body undegraded. These particular suppositories are designed to melt and absorb quickly for convenience, but release the nutrients slowly over a period of 12 hours to ensure their full absorption and usefulness in the body.
Note: Storing this product at room temperature will not alter the effectiveness or potency. However a firm suppository is necessary for a comfortable and easy insertion. Therefore we recommend that this product be stored in the refrigerator to maintain firmness. If the suppository does become soft, place the suppository in the refrigerator to achieve the firmness needed for comfortable insertion Avoid excessive heat 40°C (104°F). Store in a cool place 8° to 15°C (46° to 59°F) or refrigerate. When using nutritional supplements or nutraceuticals, please inform your physician if you are undergoing treatment for a medical condition healthcare professional.
- If pregnant, nursing, or undergoing treatment for a medical condition, consult your physician before taking this product
- Keep out of reach of children
- Do not exceed recommended dose
* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.