Quicksilver Scientific LipoCalm, Sleep & Relaxation Aid, 50 mL

List Price: $39.00
Our Price: $35.10

Quicksilver Scientific LipoCalm is a breakthrough in nutritional sleep support. If you find yourself struggling to de-stress and wind-down before bed, then this is the supplement for you. Features a proprietary liposomal blend of PharmaGABA and a number of potent botanical extracts which have displayed the potential to activate GABA receptors in the brain. Quicksilver Delivery Systems™ might aid in transporting nutritional compounds past the blood-brain barrier.

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  • GABA, skullcap, passionflower, and chamomile proprietary blend is unlike any other sleep support formula on the market.
  • May aid the body in winding down for sleep by targeting GABA neurotransmitters.
  • PharmaGABA is the highest quality natural GABA extract available anywhere.
  • Pairs well with melatonin supplementation in those who work night shifts.
  • Quicksilver Delivery Systems™ utilize liposomal emulsification to greatly enhance nutrient bioavailability.
  • 25 potent servings per container.

A Nutritional Approach to Healthy Sleep

In order to enter a deep and truly restful night’s sleep, the body must first wind-down into a state of relaxation. While our bodies have natural mechanisms in place to help this process along (such as the release of melatonin in response to decreased light exposure), there are countless factors which might intervene and leave our bodies in a state of alert or excitement well into the night. Those who work night shifts and are required to sleep through the day might find this problem to be especially persistent because they aren’t getting as much assistance from melatonin release.

While various brands of sleeping pills have become a popular solution to this problem, their potential side effects leave many in search of nutritional alternatives which provide the same utility. Thankfully, there is a vast array of nutrients which are directly linked to sleep and relaxation, and are backed by countless pages of scientific research!

Ingredients for Sleep & Relaxation Support

GABA – Of all the neurotransmitters in the human brain, none are more closely tied to sleep than GABA receptors. As one landmark review on the subject states “It is well established that activation of GABA(A) receptors favors sleep.”1 Many of the most popular hypnotic medications are designed to do exactly this.

Skullcap has benefits for natural sleep and is used in Quicksilver Scientific LipoCalm to support GABA

Skullcap, or Scutellaria

While the idea of consuming neurotransmitters might sound strange to some, GABA actually occurs naturally in certain foods, such as the popular fermented Korean dish known as kimchi. Quicksilver Scientific LipoCalm uses PharmaGABA because it is the highest quality natural GABA extract derived from the same lactic acid bacteria used in the making of kimchi. Supplements using low-cost synthetic GABA extracts are unlikely to cross the blood-brain barrier and have any tangible effect on access to relaxation and sleep.

Skullcap – Also known by its scientific name of scutellaria lateriflora, skullcap root extract is one of the most relevant natural extracts in scientific research surrounding sleep and relaxation. One study found that it was capable of improving sleep behavior in vertebrae models by way of GABA(A)-BZD receptor binding.2 Another study found skullcap, in combination with romaine lettuce extract, induced significantly enhanced global mood without a reduction in energy or cognition in healthy volunteers.3

Passionflower – Similar to other ingredients in LipoCalm, passionflower has been shown to effect GABA(A) receptors. In addition, clinical trials have revealed that this herb may have a particularly strong effect on feelings of stress and anxiety.4,5

Chamomile – Perhaps the most popular of all herbal sleep support agents. For hundreds of years chamomile tea has been recommended as a pre-bedtime drink to aid in sleep and relaxation. Some people mistakenly assume that this is only because chamomile tea is free from caffeine unlike most teas commonly found around the house. This is not the case. One study reported chamomile exhibiting benzodiazepine-like hypnotic activity in sleep-disturbed rats.6 Another study has reported a significant presence of benzodiazepine-like compounds in chamomile extracts which may be capable of effecting GABA receptors in the brain.7


Note: Store this product at Room Temperature


  • If pregnant, nursing, or undergoing treatment for a medical condition, consult your physician before taking this product
  • Keep out of reach of children
  • Do not exceed recommended dose


* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.

Supplement Facts

Serving Size: 2 mL (4 pumps)

Servings Per Container: 25

Amount Per Serving
Proprietary Blend:
Phospholipids (from purified sunflower seed lecithin), gamma-Aminobutyric acid (as PharmaGABA®), Liquid Skullcap Herb extract (Scutellaria lateriflora), Liquid Passion Flower extract (Passiflora incarnata), Chamomile Flower oil
350 mg
Other Ingredients: Water, Glycerin, Ethanol, Vitamin E (as Tocofersolan and Natural Mixed Tocopherols)

Dosage & Use

  • Take 2-4 pumps as needed.
  • Hold in mouth 30 seconds before swallowing.
  • May be mixed into water.
  • Repeat to desired dosage or as directed by healthcare professional.
  • Best taken on an empty stomach at least 10 minutes before meals.
  • Use within 60 days of opening.


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  1. GABA mechanisms and sleep.
  2. Romaine Lettuce/Skullcap Mixture Improves Sleep Behavior in Vertebrate Models.
  3. American Skullcap (Scutellaria lateriflora): a randomised, double-blind placebo-controlled crossover study of its effects on mood in healthy volunteers.
  4. Passiflora incarnata L. Improves Spatial Memory, Reduces Stress, and Affects Neurotransmission in Rats.
  5. Effects of Passion Flower Extract, as an Add-On Treatment to Sertraline, on Reaction Time in Patients ‎with Generalized Anxiety Disorder: A Double-Blind Placebo-Controlled Study
  6. Hypnotic activities of chamomile and passiflora extracts in sleep-disturbed rats.
  7. Benzodiazepine-like compounds and GABA in flower heads of Matricaria chamomilla