Pure Encapsulations Vitamin D3 VESIsorb, 60 Caplique Capsules

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Vitamin D3 VESIsorb utilizes a patented lipid-based delivery system that increases absorption & bioavailablitly. Vitamin D3 is thought to support bone, cardiovascular, colon & cellular health. Also may help with glucose metabolism and the immune system.


VESIsorb® Vitamin D offers a unique self-assembling nano-colloid system to enhance vitamin D absorption by promoting the ability of vitamin D to dissolve readily in an aqueous environment.*

Uses for VESIsorb Vitamin D:

  • Bone Health: Vitamin D promotes intestinal calcium and phosphorous absorption and reduces urinary calcium loss, essential mechanisms for maintaining proper calcium levels in the body and for healthy bone composition. Clinical studies involving vitamin D supplementation suggest the importance of vitamin D in addition to calcium for bone health. Vitamin D supplementation alone may also support bone health.*
  • Cardiovascular Support: Optimal vitamin D levels have been associated with cardiometabolic health, including healthy inflammatory balance, glucose metabolism, blood flow and antioxidant defense. This may be attributed to its effect on calcium metabolism or possibly by helping to maintain healthy plasma renin function. Preliminary evidence suggests that vitamin D may also play a role in maintaining healthy glucose metabolism, since vitamin D receptors are present on the islet cells of the pancreas.*
  • Cellular Health: Studies suggest vitamin D supports colon health by promoting healthy cellular function. Vitamin D is also believed to provide general cellular support potential, including breast and prostate cells, in part by helping to maintain healthy angiogenesis balance, supporting immune cell activity and maintaining healthy cell metabolism. Vitamin D receptors have been found on most immune cells and areas of the brain involved in memory and cognition, suggesting support for immune, nerve and cognitive function.*

Vitamin D helps the body to absorb calcium which is essential for bone formation. Vitamin D deficiency can cause rickets in children. Rickets is where bones become soft and bend. In adults, deficiency can lead to osteoporosis (fragile bones likely to break) and osteomalacia (bone pain and weak muscles).1

Aside from bone disorders, studies suggest vitamin D may help protect against certain types of cancer such as colon, prostate, and breast cancers. Researches have also found that low levels of vitamin D in pregnant women may lead to a low birth weight which may cause concerns such as premature death of the baby or the developing of various chronic conditions such as heart disease, type 2 diabetes, and high blood pressure as they get older. Low levels of vitamin D have also been linked to daytime sleepiness. The study was done on people who were diagnosed with sleep apnea. Lower levels of vitamin D were associated with higher levels of daytime sleepiness.

Enhanced Absorption Patented VESIsorb Delivery System

  • Developed by Vesifact, a Switzerland-based company dedicated to innovative technology and research
  • Patented, lipid-based delivery system increases bio availability of a bioactive that is fat soluble or that has poor water solubility
  • Self-assembling colloidal system forms evenly dispersed fluid droplets upon contact with water in the GI tract, each with a mean diameter of less than 100 nanometers and with the bioactive at its core
  • These nanosize water-soluble droplets or micelles allow the bioactive to cross the water layer of the GI tract for absorption
  • Provides extended release of the bioactive over time


Supplement Facts

Serving Size: 1 Caplique capsule

Servings Per Container: 60

Amount Per Serving
Vitamin D (as cholecalciferol)(D3) 2000 IU
Other Ingredients: medium chain triglycerides, polysorbate 80, polyglycerol fatty acid esters, vegetarian Caplique Capsule

Caplique® Capsule is a registered trademark used by Pure Encapsulations under license. Each Caplique® Capsule is preserved with a nitrogen bubble, which may give the appearance of the capsule not being full. Contents may appear cloudy or thick and may settle or separate.
VESIsorb is a registered trademark of Source One Global Partners

Dosage and Use:

  • 1-2 Caplique Capsules daily. Consume with food.

Caution: It is recommended that individuals using more than 2,000 iu vitamin D per day have their blood levels monitored. Large doses of vitamin D can cause hypercalcemia, signs include headache, weakness, nausea, vomiting, and constipation. Individuals with hyperparathyroidism or kidney disease are at particular risk. Consult your physician for more information. If pregnant or lactating, consult your physician before taking this product.

Are There Any Potential Drug Interactions? Vitamin D may result in hypercalcemia in certain individuals taking digoxin or thiazide diuretics. Consult your physician for more information.


  • If pregnant, nursing, or undergoing treatment for a medical condition, consult your physician before taking this product
  • Keep out of reach of children
  • Do not exceed recommended dose


1. MedlinePlus: Osteoporosis


* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.



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