PatchMD Immune Defense Plus Topical Patch, Liver Detox & Immune Support, 30 Patches

List Price: $30.95
Our Price: $24.95

When it comes to protecting the body from toxic overload, it’s important not to neglect the liver. The detoxification system and the production of glutathione are rooted in the liver. PatchMD Immune Defense Plus Topical Patches contain all the vitamin, mineral and antioxidant content one would expect from an immune support formula with the addition of key herbal ingredients which are known for their liver support properties.

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  • Contains essential immune support ingredients like vitamin C, vitamin D, and zinc.
  • Also features herbal liver health ingredients like licorice root, astragalus, and hesperadin.
  • Rich in antioxidants and anti-inflammatory support compounds.
  • Ideal for protecting the body from toxic overload.
  • Transdermal patch absorption may be helpful for those with gastrointestinal malabsorption issues.
  • All patches are free from common allergens like Latex, Lactose, Gluten and Sugar.
  • 30 patches per container.

Protect Your Body with PatchMD Immune Defense Plus Topical Patches

The modern world is filled with toxins. With the advent of plastics and the uptake in air pollution throughout the industrialized world, it’s no surprise that our bodies are constantly under attack from toxic pathogens. Thankfully, the human body is equipped with multiple systems and functions for finding and eliminating these pathogens before they can spread damage and imbalance throughout cells, tissues, and organ systems.

The two of the most prominent systems which protect the body from toxins are the immune system and the detoxification system which is based in the liver. While these systems are adept at keeping our bodies safe from harm, extreme toxic overload can push them past their limits. In these situations, it is especially important to keep the body well supplied on all of the necessary vitamins, minerals, and antioxidants.

Liver Health & Detox Support Ingredients

Dried licorice root.

Sadly, too many “immune support formulas” on the market ignore the invaluable role that the liver plays in managing toxic overload. PatchMD Immune Defense Plus Topical Patch is not one of these formulas. Here’s an overview of some of the liver support ingredients which put these Immune Defense Plus Topical Patches ahead of the curve:

Licorice Root – One of the most ancient staples of Chinese herbal remedies, licorice root is widely known for its antioxidant and anti-inflammatory support properties. A recent study evaluated the effects that these properties might exhibit on liver health in mice. The results indicate that licorice root has a positive effect on alcohol-damaged liver health. In particular, larger quantities of the antioxidant glutathione were observed in the liver after licorice root consumption.1

Astragalus – Yet another staple in Chinese herbal remedies, Astragalus has been extensively studied in relation to liver health. Via both in vitro and in vivo testing, one study has postulated that Astragalus aids in liver health through the inhibition of TGF-β1/Smads signaling pathway in hepatic stellate cells. This results in decreased concentrations of collagen in the liver, as well as other benefits. In addition, the same study theorizes that astragalus and licorice root work synergistically towards these ends.2

Hesperadin – A flavonoid component of citrus seeds. In vitro testing has shown that Hesperadin successfully induced human HepG2 cell apoptosis via mitochondrial pathway and death receptor pathway. Cell apoptosis actually refers to the death of cells.3 While this might sound like a negative effect, apoptosis is actually fundamental to human health and should occurring at a balanced rate in healthy tissues and organs.



  • If pregnant, nursing, or undergoing treatment for a medical condition, consult your physician before taking this product.
  • Keep out of reach of children.
  • Do not exceed recommended dose.


* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.

Supplement Facts

Serving Size: 1 Patch

Servings Per Container: 30

Amount Per Serving
Zinc Picolinate 613.47 mcg
Vitamin C 15.34 mg
Vitamin D 3.83mcg
Echinacea Purpura 3.07 mg
Echinacea Augustfolia (Root) 9.20 mg
Green Tea (Camellia Sinensis Leaves) Extract 4.60 mg
Astragalus Extract (Astragalus Membranaceus Root) 6.13 mg
Zinc Picolinate Schizandra Berry Extract (Schisandra Chinensis) 7.67 mg
Elderberry (Sambucus Nigra Fruit) 6.13 mg
Arabinogalactan (Larch Tree) 3.07 mg
Olive Leaf Extract (Olea Europaea) 15.34 mg
Bromelain (2,400 GDU/g) 2.30 mg
Maitake (Grifola frondosa) 1.53 mg
Licorice Root (Glycyrrhiza Glabra Root) 4.60 mg
Garlic (Allium Sativum Bulb) 7.67 mg
Hesperidin (Citrus Aurantium Peel Extract) 613.47 mcg
PMD Proprietary Blend
Lemon Peel (Citrus limon) 1.53 mg
Pine Bark Extract 766.84 mcg
Rutin Powder (Sophora Japonic)(Flower bud) 613.47 mcg
Prickly Ash Bark (Zanthoxylum Clava-herculis) 6.90 mg
Oregon Grap Root (Berberis Aquifolium) 2.30 mg

Dosage & Use

  • Apply patch daily to an area with little or no hair, i.e., shoulder, back or hip.
  • For best results, it is recommended to wear PatchMD patches for 8 hours.
  • There is no additional benefit wearing the patch longer than 8 hours.
  • Patches can be worn during sleep.
  • Avoid using any lotion or cream in the same area as it will inhibit absorption.
  • Patch is not waterproof.
  • It is ok to wear multiple patches at a time.


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  1. Hepatoprotective effect of licorice, the root of Glycyrrhiza uralensis Fischer, in alcohol-induced fatty liver disease
  2. Synergistic anti-liver fibrosis actions of total astragalus saponins and glycyrrhizic acid via TGF-β1/Smads signaling pathway modulation.
  3. Hesperidin from Citrus seed induces human hepatocellular carcinoma HepG2 cell apoptosis via both mitochondrial and death receptor pathways