Metagenics AdvaClear, Capsules

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AdvaClear by Metagenics utilizes a variety of nutrients to protect against free radicals generated by Phase I detoxification, renew energy, vitality and mental wellbeing. It provides the needed support for the Phase I and Phase II detoxification process.


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SKU: ADV126 Category:


  • Contains a potent blend of vitamins and antioxidants
  • Supports the function of Phase I and II detoxification pathways
  • Better detoxification can lead to better energy levels

The Importance of the Phase I and Phase II Pathways

Phase I detoxification consists of oxidation reduction and hydrolysis. Phase one detoxification is catalysed by enzymes known as the cytochrome P450 enzyme group or Mixed Function Oxidase enzymes MFO. These enzymes reside on the membrane system of the liver cells (called Hepatocytes). Simply put, this pathway converts a toxic chemical into a less harmful chemical. This is achieved by various chemical reactions (such as oxidation, reduction and hydrolysis), and during this process free radicals are produced which, if excessive, can damage the liver cells. Antioxidants (such as vitamin C and E and natural carotenoids) support the reduction of damage caused by these free radicals. If antioxidants are lacking and toxin exposure is high, the toxic chemicals in the body will become far more dangerous.

The Phase II is called the conjugation pathway, whereby the liver cells add another substance (eg. cysteine, glycine or a sulphur molecule) to a toxic chemical or drug, to render it less harmful. This makes the toxin or drug water-soluble, so it can then be excreted from the body via watery fluids such as bile or urine.


Supplement Facts

Serving Size: 2 Capsules

Servings Per Container: 63 (21)

Amount Per Serving

Vitamin A – [33% (416.67 IU) as retinyl palmitate and 67% (833.33 IU) as beta-carotene]

2500 IU

Vitamin C (as magnesium ascorbate)

133 mg

Vitamin D (as cholecalciferol)

33 IU

Vitamin E (as d-alpha tocopheryl acetate and mixed tocopherols)

67 IU

Thiamin (as thiamin mononitrate)

10 mg


5 mg

Niacin (as niacinamide and niacin)

23 mg

Vitamin B6 (as pyridoxine HCl)

17 mg

Folate (as L-5-methyl tetrahydrofolate and 5-formyl tetrahydrofolate)

268 mcg

Vitamin B12 (as cyanocobalamin)

33 mcg


66 mcg

Pantothenic Acid (as D-calcium pantothenate)

33 mg

Zinc (as zinc citrate)

6.5 mg

Selenium (as selenomethionine)

50 mcg

Copper (as copper citrate)

0.66 mg

Manganese (as manganese citrate)

1.65 mg

Molybdenum (as molybdenum amino acid chelate)

66 mcg


67 mg

Sodium Sulfate

100 mg


117 mg


Silymarin -(from milk thistle seed extract, Silybum marianum)

50 mg

Decaffeinated Green Tea (Camellia sinensis) Leaf Extract [standardized to 60% (33.6 mg) catechins and 40% (22.4 mg) epigallocatechingallate (EGCG)]

56 mg

Artichoke Leaf Extract (Cynara scolymus) – (containing cynarin and chlorogenic acid)

167 mg

Watercress Whole Plant 4:1 Extract – (Nasturtium officinale)

133 mg

Pomegranate (Punica granatum L.) Whole Fruit Extract [standardized to 45.8 mg gallic acid equivalent (GAE)]

87.5 mg

Other Ingredients: Capsule (hydroxypropylmethylcellulose), microcrystalline cellulose, magnesium stearate (vegetable), and silica

Dosage and Use:

  • Two capsules one to three times daily or as directed by your health care practitioner.


  • If pregnant or lactating, consult your physician before taking this product. Excess Vitamin A intake may be toxic and may increase the risk of birth defects.
  • Keep out of reach of children
  • Do not exceed recommended dose


* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.


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