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Life Extension Ginkgo Biloba Certified Extract, 120 mg, 365 Vegetarian Capsules

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For nearly 2800 years the Chinese have used extracts from the ginkgo biloba tree to treat a variety of conditions to maintain the healthy normal function of the brain, cardiovascular, blood and blood vessels, circulatory, and metabolic processes.

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Description

Benefits of Ginkgo Biloba Certified Extract

  • Supports healthy aging of the brain
  • Promotes healthy circulation
  • Strengthens capillaries
  • Supports healthy oxygen and glucose metabolism in the brain
  • Helps maintain healthy blood vessels
  • Contains less than 1 ppm ginkgolic acid

Ginkgo biloba is one of the oldest trees known and has been used to support health for nearly 2,800 years to treat a variety of conditions to maintain the healthy normal function of the brain, cardiovascular, blood and blood vessels, circulatory, and metabolic processes.1-11 The ancient formulas have been studied by scientists and reformulated to be as safe and effective as possible.12-21

Ginkgo leaf extracts contain several active constituents with neuroprotective and cardioprotective properties. These include flavonoids (e.g., rutin, quercetin, kaempferol, and proanthocyanidins), terpenoids (i.e., ginkgolides), and organic acids. Flavonoids are known to strengthen capillaries, promote healthy blood flow to the brain, and help maintain cognitive health.22-26

In a study to determine whether ginkgo extract could prevent age-associated cellular changes, the brain and liver mitochondria of old mice fed ginkgo extract in their drinking water was compared to those of young and old control mice. Mitochondria from the mice given ginkgo exhibited significantly less genetic damage, peroxide generation, and oxidation of the crucial antioxidant glutathione than non-supplemented mice. In addition, mitochondria from old mice given the ginkgo extract resembled those of young mice much more closely, being similar in size and morphology. The study concluded that standardized ginkgo extract prevents age-related decline in mitochondrial structure and function by protecting mitochondria from oxidative damage.29

Ginkgo Biloba Certified Extract was designed to exceed the worldwide standards of ginkgo purity. The health regulatory agency in Germany mandates that ginkgo cannot contain more than 5 ppm of ginkgolic acid, and only ginkgo formulas that meet these standards are included in the clinical studies that have shown such great health results from ginkgo. Ginkgolic acid is a natural part of the ginkgo plant, and is similar to the anacardic acid in poison ivy which causes allergic reactions in some people. Formulas with less than 5 ppm of the ginkgolic acid are safe and do not cause poison ivy like effects. Ginkgo Biloba Certified Extract contains less than 1 ppm ginkgolic acid, making it one of the lowest ginkgolic acid levels commercially available in a ginkgo leaf supplement.30-34

Flavonoids such as quercetin and kaempferol from Ginkgo biloba are potent antioxidants and scavengers of many species of free radical, protecting against oxidative cell damage.27-28 Ginkgo protects the energy-producing mitochondria in the cells, thus enhancing oxygen utilization and cellular respiration.18 Ginkgo may also inhibit production of pro-inflammatory cytokines IL-1beta and TNF-alpha while upregulating the production of an anti-inflammatory cytokine called IL-10.35,36

The premium-quality biochemical extract in Ginkgo Biloba Certified Extract has been concentrated and dual-standardized to ensure the highest quality, consistency and biological activity.

 

Supplement Facts

Serving Size: 1 vegetarian capsule

Servings Per Container: 365

Amount Per Serving

Ginkgo biloba (leaf) extract [std. for 24% ginkgo flavone glycosides, 6% total terpene lactones, <1ppm ginkgolic acid]

120 mg

Other Ingredients: microcrystalline cellulose, vegetable cellulose (capsule), stearic acid.

Dosage and Use:

  • Take one capsule daily with or without food, or as recommended by a healthcare practitioner.

Caution: If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product.

Warnings:

  • If pregnant, nursing, or taking medication, consult your physician before taking this product
  • Keep out of reach of children
  • Do not exceed recommended dose

References:

1. Phytother Res. 2008 Jun;22(6):734-9.
2. Phytomedicine. 2008 Mar;15(3):164-9.
3. Clin Physiol Funct Imaging. 2002 Nov;22(6):375-8.
4. Wilderness Environ Med. 2007 Winter;18(4):251-7.
5. J Pharm Pharmacol. 2006 Feb;58(2):243-9.
6. Asian J Androl. 2011 Sep;13(5):742-6.
7. Neuroscience. 2007 Jan 5;144(1):217-22.
8. Clin Chim Acta. 2004 Feb;340(1-2):153-62.
9. Acta Pharmacol Sin. 2008 Sep;29(9):1042-50.
10. J Nat Med. 2011 Jan;65(1):50-6.
11. Pharmacopsychiatry. 2003 Jun;36 Suppl 1:S89-S94.
12. Phytomedicine. 2007 Feb;14(2-3):196-203.
13. Acta Pharmacol Sin. 2004 Oct;25(10):1306-11.
14. Clin Nutr. 2004 Aug;23(4):615-21.
15. Clin Lab Haematol. 2003 Aug;25(4):251-3.
16. Thromb Res. 2009 Jul;124(3):328-34.
17. Altern Ther Health Med. 2001 Sep-Oct;7(5):70-86, 88-90.
18. Platelets. 2010;21(5):373-9.
19. Adv Ther. 1998 Jan-Feb;15(1):54-65.
20. Acta Neurobiol Exp (Wars). 2009;69(2):217-31.
21. Pharmacopsychiatry. 2010 May;43(3):86-91.
22. J Chromatogr A. 2009 Mar 13;1216(11):2002-32.
23. Drugs R D. 2003;4(3):188-93.
24. Wien Med Wochenschr. 2007;157(13-14):295-300.
25. Arzneimittelforschung. 2007;57(1):4-11.
26. Rev Prat. 2000 Jun 1;50(11):1195-8.
27. Planta Med. 2009 Jun;75(8):792-6.
28. Yao Xue Xue Bao. 2007 Sep;42(9):930-4.
29. Pharmacol Res. 2007 Dec;56(6):493-502.
30. Pharmacol Res. 2002 Dec;46(6):565-8.
31. Adv Ther. 1998 Jan-Feb;15(1):54-65.
32. Chem Biol Interact. 2009 Sep 14;181(1):115-23.
33. Ophthalmol Clin North Am. 2005 Dec;18(4):597-609.
34. Pharmacopsychiatry. 2003 Jun;36 Suppl 1:S89-94
35. Ginkgo biloba for cerebral insufficiency.
36. NIH: Ginkgo

 

* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.

 

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