Life Extension Arginine Ornithine Powder, 150 grams

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Life Extension Arginine Ornithine Powder contains ingredients that supports ammonia detoxification, the immune system, and the heart and arteries. It may provide support for healthy tissue and bone, increased strength and muscles, and help stimulate.

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L-arginine is a semi-essential amino acid involved in numerous areas of human biochemistry, including ammonia detoxification, hormone secretion, and immune modulation. Arginine is also well known as a precursor to nitric oxide (NO), a key component of endothelial-derived relaxing factor, an endogenous messenger molecule involved in a variety of endothelium-dependent physiological effects in the cardiovascular system.

L-ornithine is a metabolite of arginine in the body, formed as a byproduct of the action of the arginase enzyme on arginine.66 L-arginine is required for the body to synthesize nitric oxide,67,68 which enables the arterial system to retain its youthful elasticity. Nitric oxide also helps to produce an endothelial-derived relaxing factor, which is needed by the arterial system to expand and contract with each heartbeat.69-78

L-arginine may also help stimulate the immune system.79-83

Surgical or traumatic injury greatly increases the body’s need for L-arginine, a key building block to maintaining healthy tissue and bone. L-ornithine may also be used for this purpose.84-94

Some studies suggest that either independently or combined, arginine and ornithine appear to stimulate growth hormone (GH) based on the increase in strength and muscle mass that was produced while intensely working out.95-97 Other research evidences ornithine’s ability to stimulate GH release.98-103 Another study showed a combination of ornithine with acetyl-L-carnitine enhanced the GH release feedback loop.104 However, studies suggest that low doses of L-arginine and/or L-ornithine are unlikely to effect GH release. A minimum dose of L-arginine to promote GH release is probably 5 to 9 grams.96

L-arginine and L-orinithine are used for heart and blood vessel conditions such as congestive heart failure, angina, high blood pressure, and coronary artery disease.1 Blood vessels relax due to the nitric oxide and this may improve circulation.4 Other uses include increasing muscle, total strength and lean body mass.2 The combination also supports the body’s ability to stimulate growth hormone.3


Supplement Facts

Serving Size: 1 level teaspoon (approx. 3.1 g)

Servings Per Container: about 48

Amount Per Serving
L-Arginine hydrochloride 2.25 g
L-Ornithine hydrochloride 750 mg
Other Ingredients: none

Dosage and Use:

  • Take one level teaspoon on an empty stomach, or as recommended by a healthcare practitioner.


  • If pregnant, nursing, or taking medication, consult your physician before taking this product
  • Keep out of reach of children
  • Do not exceed recommended dose


1. MedlinePlus: L-arginine
2. Effects of arginine and ornithine on strength, lean body mass and urinary hydroxyproline in adult males.
3. Arginine and ornithine supplementation increases growth hormone and insulin-like growth factor-1 serum levels after heavy-resistance exercise in strength-trained athletes.
4. WebMD: Arginine: Heart Benefits and Side Effects
64. Srp Arh Celok Lek. 2009 Nov-Dec;137(11-12):594-600. Serbian.
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95. J Strength Cond Res. 2010 Apr;24(4):1082-90.
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97. J Sports Med Phys Fitness. 1989;29(1):52-6.
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* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.



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