Empirical Labs Liposomal Reduced Glutathione, 4 oz Liquid

Our Price: $89.00

Empirical Labs Liposomal Reduced Glutathione uses all natural non-hydrogenated phosphatidylcholine liposomes for delivery. The uniformity in size ensures optimal absorption for maximum nutrition. Glutathione is the most potent and versatile antioxidant.

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Empirical Labs Liposomal Reduced Glutathione uses all natural non-hydrogenated phosphatidylcholine liposomes for delivery. The uniformity in size ensures optimal absorption for maximum nutrition. Reduced Glutathione is the most potent and versatile antioxidant.

Empirical Labs uses natural Phosphatidylcholine liposomes as a delivery method for Reduced Glutathione.

They believe that each and every component of their products must be as health building as possible. Current literature has shown that hydrogenated liposomes strongly increased LDL (bad) cholesterol levels while natural non-hydrogenated phosphatidylcholine was shown not to alter cholesterol levels in primates.

Empirical Lab’s liposomes:

  • All natural ingredients
  • Uniform liposomes at 150 nm particle size
  • 500 mg reduced glutathione per dose
  • 400 mg all natural phosphatidylcholine per dose (not hydroxylated, hydrogenated, nor “essential” phospholipids)
  • Scientifically studied structure
  • Scientifically studied liposomal delivery method

This product has only what you need:

  • Reduced Glutathione (nutrition)
  • Natural phosphatidylcholine (delivery method and nutrition)
  • Purified water
  • Natural flavors and preservative

The Liposome’s structure:

Empirical Labs takes great care to process their liposomes properly in order to generate properly structured spherical liposomes in our product. If the structure is not there, they are not liposomes.

Introduction to Glutathione (GSH)

Considered to be the body’s most important self-generated antioxidants, glutathione (GSH) is also the most potent and most versatile. There are many roles GSH play in our health including:

  • GSH is found in nearly every living cell in our bodies. Some of the highest concentrations are located in organs such as the liver, pancreas, spleen, kidneys, and the lens and cornea of the eye.
  • This very powerful antioxidant prevents the formation of free radicals and renders existing free radicals ineffective.
  • Aids in the production of white blood cells which affects our immune system. Therefore, GSH is one of the most potent anti-viral agents known.
  • Out of all the anti-cancer agents the body manufactures, GSH is the strongest.
  • Glutathione has the ability to return oxidized Vitamin C and Vitamin E back to their original unoxidized state.
  • The liver utilizes glutathione to detoxify acetaminophen, benzpyrene, formaldehyde, and many other toxins and carcinogens.
  • The brain requires GSH for normal, healthy function.
  • It maintains the congruity and purity of the red blood cells.
  • As we age, glutathione begins to diminish. By increasing GSH levels, the aging process can be slowed and cellular differentiation can take place.
  • Glutathione assists in creating nucleic acid and repairing DNA. It is also a required antioxidant to protect all our proteins.
  • GSH helps to maintain the redox potential of a cell.

GSH and Therapeutics

  • Detoxification
    • Heavy metal toxicity including mercury, lead, arsenic and cadmium
    • Common toxins that glutathione may help protect against are car exhaust, cigarette smoke, aspirin and alcohol (Marz, p. 78, 1997)
    • Pesticide and industrial chemical exposure
    • Steroids
    • Bacterial toxins (Clostridia difficile)
    • Pharmaceuticals (very long list that need to be detoxified by the liver) (Marz, p. 79, 1997)
  • Immune enhancement: 1-3 grams per day. This is especially effective against clostridium in the GI. It helps prevent translocation.
  • Psoriasis
  • Diabetes mellitus: Especially in ketosis as DM patients will generally excrete increased amounts of sulfur containing amino acids.
  • Liver disease including cirrhosis and fatty liver disease caused by alcohol: Studies show mild effects at large doses.
  • Ulcers intestinal or stomach: In patients with stomach ulcers low levels of GSH have been found.
  • Aspirin or phenacetin overdose (useful for rheumatoid arthritis patients or chronic pain sufferers on 8 or more aspirin/day).
  • Hematological conditions: myelofibrosis, acute leukemia, chronic myelocytic leukemia, lymphoma, polycythemia vera.
  • Alcoholism.
  • Before ionizing radiation therapy.
  • Cataracts.
  • Parkinson’s disease, Alzheimers, ALS, MS and other neurologic conditions including Autism/Pervasive Developmental Delay.
  • Chronic kidney failure.

GSH and Metabolism

  • Glutathione is synthesized in the body from 3 amino acids: Cysteine, glutamine and glycine. Cysteine is one of the sulfur containing amino acids used for the synthesis of glutathione, which is very critical in detoxification. N Acetyl Cysteine (NAC) is the rate limiting amino acid for the production of glutathione within the cells of the body, has mucolytic properties, and is a powerful antioxidant and detoxifier. Some research indicates that NAC is more readily absorbed into certain cells of the body than glutathione and is therefore an excellent synergist with glutathione. The thiol group is the active part of the molecule which serves as a reducing agent to prevent oxidation of tissues.
  • Reduced Glutathione: Glutathione acts as one of the major detoxifiers in the body, but it must be in the reduced form to work properly. Sometimes glutathione will be listed on the label of a product, however it wont be specifically listed as being reduced. The unreduced form is much cheaper and isn’t metabolically active. Riboflavin, niacinamide, selenium, lipoic acid and glutathione reductase are all essential cofactors for generating reduced glutathione. Once the cysteine moieties become oxidized, they combine to form cystine. Cystine taken by itself is poorly absorbed.
  • Glutathione peroxidase is another compound which is involved in detoxification against peroxides and other xenobiotics. It is synthesized from selenium and cysteine.
  • There are no known toxicity issues or contraindications.

Cataracts: Glutathione as a Protective Bio-Mechanism

A healthy eye contains glutathione in very high concentrations, whereas low levels adversely affect the eye. Glutathione maintains the water balance in the lens. It is synthesized in the lens (and elsewhere) and is essential to normal metabolism. Glutathione can benefit lens function by:

  • Preserving the physicochemical integrity of proteins in the lens
  • Maintaining action of the sodium-potassium transport pump and molecular integrity of lens fibers (protein)
  • Maintaining molecular integrity of lens fiber membranes and acting as a free radical scavenger to protect membranes and enzymes from oxidation
  • Preventing free-radical-induced photochemical generation of harmful by-products
  • Reactivating oxidized vitamin C, which improves antioxidant capability in the lens




  • If pregnant, nursing, or taking medication, consult your physician before taking this product
  • Keep out of reach of children
  • Do not exceed recommended dose

* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.


Supplement Facts

Serving Size: 4 milliliters

Servings Per Container: 30

Amount Per Serving
Reduced Glutathione 500 mg
Natural (non-hydrogenated) Phosphatidylcholine 400 mg
Other Ingredients: Purified water, natural flavors, potassium sorbate.


Dosage & Use

  • 4 milliliters daily (just over one teaspoon) or as directed by your healthcare provider
  • Mix into one ounce of juice as a palatable way to ingest
  • Gently shake before using
  • Refrigerate after opening
  • Use within 40 days of opening


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1. Glutathione metabolism and its implications for health.
2. Metabolism and functions of glutathione in brain.