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Zetpil Melatonin, 400 mg, 12 Hour Sustained Release Formula Suppositories, 30 Count

Item Number: MLTSR2 | Be the first to review this product!

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List Price: $240.00
Our Price: $189.95
Your Savings: $50.05
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Supplement Overview

Item Catalog Number: MLTSR2
30 Suppositories
Click for Research Links
Click to View Supplement Facts
How to Insert a Suppository
All Suppositories and Creams

These melatonin suppositories are designed to provide exceptional sleep support and antioxidant activity. Though melatonin supplements have outstanding nutritional benefits, experts believe that the bioavailability of orally ingested melatonin is extremely low. This suppository base is designed to dissolve fast and release slow for optimal convenience and superior absorption rates.

  • 400 mg dose of highest quality melatonin designed for maximum bioavailability
  • Potent antioxidant with anti-inflammatory properties
  • May aid in the development of a healthy sleep cycle
  • No degradation through digestion as with oral supplements
  • Made of an all-natural proprietary suppository base


The Multiple Benefits of Melatonin Supplementation

Most people turn to melatonin supplements as a way to support the development of a regular sleep schedule. The production of melatonin in the pineal gland is an intricate process which has a dramatic effect on healthy sleep and energy levels. In fact, it has been found that melatonin is produced at higher rates in the dark to prepare the body for sleep and at lower rates in the light to support energy levels through the day. Those who find themselves unable to maintain a regular sleeping schedule, either for personal health or work related reasons, may discover that melatonin supplementation provides natural support for a healthier sleep cycle.

While melatonin is very commonly taken for nutritional sleep support, it is much less widely known that melatonin is one of the most effective antioxidants in the human body. The presence of melatonin in the bloodstream supports the neutralization of free radicals and thus inhibits the development of oxidative stress. It has also been extensively studied for its anti-inflammatory properties.1,2


Improving the Absorption Rates of Melatonin

Melatonin is a powerful nutrient which provides sleep support and antioxidant properties. However, experts question whether or not these benefits can be fully harnessed from melatonin which is ingested orally. The problem with capsule, liquid, or chewable varieties of melatonin supplements is that they are required to pass through the digestive tract where the majority of the melatonin content is damaged and degraded. In fact, the bioavailability of oral melatonin has been extensively studied and shown to be exceptionally poor, particularly in small doses (2-4 mg).3

Melatonin in suppository form seems to be the most effective means for promoting the absorption and utilization of this powerful nutrient in the body. These suppositories are designed to release slowly into the highly porous tissues of the lower bowels, bypassing the digestive system entirely and arriving in the bloodstream undiluted. The suppository base is formulated to dissolve and absorb quickly for convenience, but release the nutrients slowly over a time frame of 12 hours to promote their full absorption and usefulness within the body.

Are the Suppositories Heat Sensitive?

The suppositories do not need to be refrigerated as heat will not affect their quality or potency. The suppository base is a superior form that uses an inclusion formula with heat stable ingredients. Nonetheless, we do give the option of purchasing ice, as some customers prefer it that way. Refrigeration is for "hardening" the suppository to facilitate insertion.


Supplement Facts

Serving Size: 1 suppository
Servings Per Container: 30

Amount Per Serving

Melatonin

400 mg

Suppository Base: The base is a proprietary combination of plant and fruit butters, vegetable acids, medium chain triglycerides, phospholipids, lecithin, vegetable starches, cellulose, oligosaccharides derivatives, polysaccharides and cycloamylose derivatives.

Other Ingredients: This product contains an extract from soybean.


Dosage and Use:

  • 1 in the early evening 2 hours before bedtime or as directed by your health care professional.
  • Some individuals become drowsy immediately and should adjust the time when they take the product accordingly.
  • This product’s potential therapeutic effect is best realized when taken overnight where the release time occurs over an 11 hour period of time. This allows Melatonin to be released into the blood stream and exert a safe, prolonged beneficial/therapeutic effect.
  • It is recommended that you always attempt to move your bowels prior to inserting the suppository(s) to avoid discharging of the suppository before the suppository can be totally absorbed.
  • It is recommended that the suppository be retained for approximately 6 hours to insure adequate absorption of the nutraceutical, herbal and nutrient ingredients contained herein. Therefor it is best when taken before bedtime.
  • To facilitate insertion it is recommended you moisten suppository with warm water.
  • If inserted while lying on one’s side, consider remaining in the supine position for 1-3 minutes following insertion.


Research Links:



References:

1. Melatonin Anti-Inflammitory Study
2. Melatonin Antioxidant Study
3. Oral Melatonin Bioavailability


* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.


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