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Zetpil Melatonin, 25 mg, Super Antioxidant Ultra Absorbable Deep Penetrating Cream, 1 oz Bottle

Item Number: PANMT02 | Be the first to review this product!

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List Price: $40.00
Our Price: $34.95
Your Savings: $5.05

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Supplement Overview

Item Catalog Number: PANMT02
1 oz Bottle
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All Suppositories and Creams

Melatonin is best known for its significant role in regulating sleep cycles. It is less known for possessing substantial antioxidant and anti-inflammatory properties. This highly bioavailable cream formulation of Melatonin from Zetpil is designed to provide superior absorption rates when compared to oral intake.

  • Precision dose (25 mg) of the highest quality melatonin
  • A potent antioxidant and free radical scavenger
  • Has been extensively studied for potential anti-inflammatory support
  • May be helpful in developing a healthy sleep cycle
  • Bypasses degradation in digestive tract that occurs with oral supplements
  • Provides deep penetrating absorption through the skin in an all-natural, topical cream

Basic Melatonin Sleep Support Facts

Melatonin is a naturally occurring hormone which is generated in the pineal gland of the human body. The primary role of Melatonin in the body is to regulate a healthy sleep cycle. Human bodies generate melatonin at an accelerated rate in the dark to prepare for sleep, and at a decelerated rate in the light in order to support energy levels and alertness throughout the day. Those who may be experiencing difficulties with keeping a regular sleep schedule, or who find themselves losing energy and focus in the daytime, might be subject to defects in their melatonin production.1

While melatonin is naturally produced in the human body, it can also be obtained in small quantities from a number of common foods like oranges, olive oil, and rice. Due to the bioavailability of melatonin from food sources being so low, certain situations require larger and more targeted doses. To attend to this demand for superior intake of melatonin, the hormone has long been synthesized for use in dietary supplements that are designed to provide a variety of doses and improved overall bioavailability.

Melatonin’s Antioxidant and Anti-Inflammatory Properties

It’s undeniable that melatonin is best known for its role in regulating sleep cycles. However, this often causes people to overlook the fact that melatonin is one of the most effective antioxidants available for dietary supplementation. In fact, melatonin is thought by many experts to be a powerful agent for supporting the body’s resistance to free radicals and the proliferation of oxidative stress. In addition to this, melatonin is thought to posses anti-inflammatory properties.2,3 Melatonin is well worth supplementing for regardless of the health of one’s sleep cycle.

Melatonin is considered to be one of the most effective and easily absorbed antioxidants on the supplement market.4 However, capsule forms of melatonin offer very poor absorption rates because they must pass through the digestive tract where their potency is heavily degraded. This cream based melatonin supplement greatly improves upon these rates by bypassing the digestive tract via direct absorption through the skin.

Supplement Facts

Serving Size: 1 to 1-1/4 ml (teaspoon)

Amount Per Serving

N­Acetyl­5­Methosytryptamine (Melatonin)

25 mg

Cream Base: Purified water, PEG=­sorbitan monolaurate, 2, 3, 4 hydroxypropane, helianthus annuus seed oil, tinctorius seed oil, cocoa butter, theo­ broma cacao, coconut oil, wheat germ oil, shea butter medicine, aloe, lecithin, mixed phospholipids, poly­saccaride derivatives, rosemary oil extract, citrus seed extract, citric acid, potassium sorbate, cyclotheptaamylose.

Dosage and Use:

  • Apply 1 to 1–1/4 ml (teaspoon) 1 to 2 times per day on clean, dry skill or as directed by healthcare professional.
  • For Topical Use only.
  • Avoid eyes and mucous membranes.
  • Zetpil advises deep penetrating cream customers, particularly men, to have an adequate amount of hairless skin area where the cream can be applied. The hair prevents the cream from being applied directly to the skin and therefore decreases the dosage which can be directly absorbed into the skin. If you are using multiple creams it not only requires more hairless areas for application, but if you have fewer hairless sites for application it requires more applications over a longer period of time. It is not advisable to apply more than one cream to any given area at the same time, and we recommend allowing an hour between applications so each can be absorbed fully.
  • For Zetpil Cosmeceuticals it is advised to apply creams directly to your face, neck and hands. Other Zetpil deep penetrating creams are most effectively absorbed when applied to the inner thigh, inner arm, back, anywhere there is minimal hair growth.

Contraindications: This product is contraindicated in persons with known hyper­sensitivity to phospholipids, sesame seeds or any of the ingredients.

Research Links:


  • If pregnant, nursing, or undergoing treatment for a medical condition, consult your physician before taking this product.
  • Keep out of reach of children.
  • Do not exceed recommended dose.

1. Melatonin Information
2. Melatonin Anti-Inflammitory Study
3. Melatonin Antioxidant Study
4. Melatonin Effectiveness Study

* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.

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