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Zetpil Calcium and Magnesium Suppositories, 30 Count

Item Number: CM01 | Be the first to review this product!

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List Price: $60.00
Our Price: $49.95
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Supplement Overview

Item Catalog Number: CM01
30 Suppositories
Click to View Supplement Facts
How to Insert a Suppository
All Suppositories and Creams

These calcium and magnesium suppositories provide the recommended dietary allowance (RDA) levels of elemental calcium and magnesium in their most bioactive forms. Magnesium deficiency has an effect on the absorption and release of calcium - one of the most important minerals for the body. Suppository form ensures proper absorption of both crucial minerals.

  • Provides RDA levels of highly absorbable calcium and magnesium
  • Calcium and magnesium are absorbed directly so they can support the body on a cellular level
  • Provides 80-85% absorption via suppository form, unlike oral supplements that degrade through digestion
  • Excellent supplement for those with sensitive digestion or poor absorption issues.
  • Made with a superior suppository base consisting of a proprietary combination of plant and fruit butters

Why Calcium and Magnesium Should be Taken Together

Even though you do not need to take magnesium and calcium together in the same supplement to absorb calcium, the body needs magnesium to properly use or metabolize calcium. This has to do with what happens to calcium after it has been absorbed, not with calcium absorption itself.1

Magnesium plays many roles in human physiology, including calcium metabolism. Magnesium deficiency impairs secretion of PTH which increases absorption of calcium in the gut by activating vitamin D3. The PTH also triggers release of calcium from the bone when the blood levels of calcium fall too low to meet the body's physiological calcium requirements. At the same time, activation of vitamin D3 requires magnesium, because the enzyme that catalyzes this activation needs magnesium to work most effectively.

Calcium is important for cellular functions, but excess calcium inside the cells can be harmful. Magnesium prevents excess calcium from accumulating inside cells. Interestingly, when cells contain too much calcium, the blood may not have enough. Even if you're taking calcium supplements, without adequate intake of magnesium the body can still develop a calcium deficiency, and all of the health complications and imbalances which that might entail. Because of this and because of its own powerful nutritional benefits, the importance of magnesium supplementation cannot be overstated.2

The bottom line is that we need magnesium to make proper use of calcium. In fact, taking calcium supplements may increase the need for magnesium by increasing the proportional intake of calcium relative to magnesium. Many people, especially seniors, consume less than the recommended daily intake (RDI), as shown in nutritional surveys. Therefore when taking 1000 mg or more of elemental calcium via diet or calcium in supplements, as is widely recommended, without magnesium the calcium to magnesium ratio may become imbalanced and therefore magnesium is included to maintain the optimal ratio.3,4

Are the Suppositories Heat Sensitive?

The suppositories do not need to be refrigerated as heat will not affect their quality or potency. The suppository base is a superior form that uses an inclusion formula with heat stable ingredients. Nonetheless, we do give the option of purchasing ice, as some customers prefer it that way.

Supplement Facts

Serving Size: 1 Suppository
Servings Per Container: 30

Amount Per Serving

Elemental Calcium

160 mg

Elemental Magnesium

40 mg

Suppository Base: The base is a proprietary combination of plant and fruit butters, vegetable acids, medium chain triglycerides, phospholipids, lecithin, vegetable starches, cellulose, oligosaccharides derivatives, polysaccharides and cycloamylose derivatives.

Other Ingredients: This product contains an extract from soybeans.

Dosage and Use:

  • 2 to 3 suppositories per day or as directed by your health care professional.
  • It is recommended that you always attempt to move your bowels prior to inserting the suppository(s) to avoid discharging of the suppository before the suppository can be totally absorbed.
  • It is recommended that the suppository be retained for approximately 10-15 minutes to insure adequate absorption of the nutraceutical, herbal and nutrient ingredients contained herein.


1. Paunier, L. Effect of magnesium on phosphorus and calcium metabolism. Montasschr Kinderheilkd 1992; 140(Suppl): S17-S20.
2. Cashman, K. Optimal nutrition: calcium, magnesium and phosphorus. Proceedings of the Nutrition Society 1999; 58:477-87.
3. Morgan, K.E.A., Magnesium and calcium dietary intakes of the U.S. population. Journal of the American College of Nutrition, 1985. 4: p. 195-206.
4. Celotti, F. Bignamini, A. Dietary calcium and mineral/vitamin supplementation: a controversial problem. The Journal of International Medicinal Research 1999; 27:1-14.

* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.

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