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Life Extension Vitamin C with Dihydroquercetin, 1000 mg, 250 Tablets

Item Number: 00927 | Be the first to review this product!

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Supplement Overview

Item Catalog Number: 00927
250 Tablets
Also available: 60 Tablets
Click to View Supplement Facts

Life Extension Vitamin C with Dihydroquercetin scavenges free radicals in the body and protects tissues from oxidative stress. Vitamin C is quickly oxidized and excreted by the body, the addition of Dihydroquercetin allows for optimal effectiveness.

Vitamin C, or ascorbic acid, is a white, crystalline, water-soluble substance found in citrus fruits. As an antioxidant, vitamin C scavenges free radicals in the body and protects tissues from oxidative stress.1-8 Vitamin C also promotes the absorption of iron, while preventing its oxidation.9,10 Vitamin C is a vital cofactor to the formation of collagen, the connective tissue that supports arterial walls, skin, bones, and teeth.5-7

More vitamin C is contained in the adrenal glands than any other organ in the body and is required at higher levels during times of stress.11-14 Physical stresses on the body such as ingestion of heavy metals,15-20 cigarette smoking,21-24 immune impairment,25-31 extreme temperatures,32-36 and chronic use of certain medications such as aspirin also signal the need for increased intake of vitamin C.37

Along with ascorbic acid, vitamin C also comes in at least two other forms: chemically bonded to minerals as ascorbates, and as the fat-soluble ascorbyl palmitate.38-40 Both of these forms are non-acidic.

In fact, a major immune-supporting activity of vitamin C is boosting glutathione levels in human lymphocytes,41 cells that make up about 25% of all white cells in the blood.

Because humans do not manufacture vitamin C internally, it must be obtained through dietary sources or supplements. Few people realize, however, that vitamin C is a water-soluble nutrient that is quickly oxidized and excreted by the body,42 which limits its efficacy. Until now, those seeking to capture vitamin C’s optimal health benefits have had no choice but to consume it several times throughout the day.

Fortunately, a flavonoid antioxidant known as dihydroquercetin functions as a vitamin C “supercharger.” Studies demonstrate that dihydroquercetin acts to inhibit the oxidation of vitamin C, thereby helping to maintain its concentration and recycle vitamin C throughout the body.43,44 This synergistic relationship between dihydroquercetin and vitamin C45 greatly enhances the efficacy of both molecules in the body’s organs and tissues. Vitamin C with Dihydroquercetin was formulated for those seeking to obtain optimal efficacy and antioxidant protection from a vitamin C supplement.

Supplement Facts

Serving Size: 1 tablet

Servings Per Container: 250

Amount Per Serving

Vitamin C (as ascorbic acid)

1000 mg

Dihydroquercetin-3-rhamnoside [from Grape (Vitis vinifera) Extract (leaf)]

10 mg

Other Ingredients: microcrystalline cellulose, stearic acid, croscarmellose sodium, vegetable stearate, silica, hydroxypropyl methylcellulose, glycerin.

This product contains NO: milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, corn or rice. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.

Dosage and Use:

  • Take one tablet daily with food, or as recommended by a healthcare practitioner.


  • If pregnant, nursing, or taking medication, consult your physician before taking this product
  • Keep out of reach of children
  • Do not exceed recommended dose


1. Indian J Exp Biol. 1997 Mar;35(3):264-6.
2. Am J Clin Nutr. 1996 Jun;63(6):985S-990S.
3. FASEB J. 1995 Apr;9(7):526-33.
4. J Am Coll Nutr. 1995 Apr;14(2):124-36.
5. Altern Med Rev. 2003 Nov;8(4):359-77.
6. J Invest Dermatol. 2002 Apr;118(4):565-72.
7. Yale J Biol Med. 1985 Nov-Dec;58(6):553-9.
8. Free Radic Biol Med. 2007 Sep 1;43(5):853-9.
9. Clin Physiol Biochem. 1986;4(1):78-86.
10. Int J Vitam Nutr Res. 1980;50(3):301-8.
11. Res Vet Sci. 1981 Sep;31(2):219-23.
12. In Vivo. 1994 Nov-Dec;8(6):1079-85.
13. Anesteziol Reanimatol. 1990 Sep-Oct;(5):71-4.
14. Psychopharmacology (Berl). 2002 Jan;159(3):319-24
15. Chem Biol Interact. 2001 Jul 31;137(1):75-88.
16. Mutat Res. 1990 Jul;241(3):305-12.
17. Environ Mol Mutagen. 1993;21(3):229-36.
18. Exp Lung Res. 1998 Mar-Apr;24(2):219-32.
19. J Nutr. 1994 Jun;124(6 Suppl):981S-986S.
20. Biomed Environ Sci. 1998 Mar;11(1):7-14.
21. Toxicology. 2002 Nov 15;180(2):121-37.
22. Environ Health Perspect. 2000 Feb;108(2):105-8.
23. Indian J Public Health. 1998 Jan-Mar;42(1):20-3.
24. Prog Food Nutr Sci. 1991;15(4):183-217.
25. Acta Obstet Gynecol Scand. 2007;86(7):783-7.
26. J Am Coll Cardiol. 2003 Nov 5;42(9):1656-62.
27. J Pediatr Gastroenterol Nutr. 2003 Jul;37(1):53-62.
28. Cancer Sci. 2003 Apr;94(4):378-82.
29. Adv Ther. 2002 May-Jun;19(3):151-9.
30. Br J Dermatol. 1980 Jan;102(1):49-56.
31. Respir Med. 2007 Aug;101(8):1770-8.
32. Indian J Med Res. 2002 Jul;116:29-34.
33. Indian J Med Res. 1993 Aug;98:178-84.
34. Vopr Pitan. 1978 Jan-Feb;(1):44-8.
35. J Nutr. 1989 Mar;119(3):425-7.
36. Tohoku J Exp Med. 1967 Jun;92(2):207-19.
37. Med Sci Monit. 2001 Jul-Aug;7(4):592-9.
38. PLoS Med. 2005 Sep;2(9):e307
39. Am J Clin Nutr. 1988 Sep;48(3):601-14.
40. J Food Tech. 1969;4:255-67.
41. Am J Clin Nutr. 2003 Jan;77(1):189-95.
42. PLoS Med. 2005 Sep;2(9):e307.
43. Free Radic Biol Med. 1995 Jul;19(1):45-52.
44. Int. J Food Sci. Tech. 1969;4:255-67.
45. Free Radic Biol Med. 1997;22(4):669-78.
46. [Antioxidant properties of dihydroquercetin].
47. Office of Dietary Supplements: Vitamin C

* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.

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