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BioGenesis 5 MTHF Activated, 30 Vegetarian Capsules

Item Number: 2365 | Be the first to review this product!

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Our Price: $33.09

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Supplement Overview

Item Catalog Number: 2365
30 Vegetarian Capsules
Click for Research Links
Click to View Supplement Facts

BioGenesis 5 MTHF Activated, with active ingredient glucosamine sulfate, may be able to help provide pain relief for those with osteoarthritis of the knee, hip, or spine. May also help to relieve pain for those with TMJ (tempromandibular joint) arthritis.

Glucosamine sulfate has been vigorously studied for its effects on osteoarthritis. According to one study, patients suffering from osteoarthritis received glucosamine sulfate, as well as additional supplements, and many reported an average of 20% pain reduction in the knee for the following 24 weeks.8

5 MTHF Activated may help to reduce the need for total knee replacement surgery, as its key ingredient, glucosamine, is a key building block in the making of cartilage tissue.9,10

By taking glucosamine sulfate, some people have reported relief from pain associated with TMJ arthritis for up to 90 days after their last dose of the supplement.10

It is possible that 5 MTHF Activated may help to promote healthy levels of homo-cysteine, dopamine, and serotonin.11

  • May be able to relieve pain associated with osteoarthritis of the knee, hip, and spine.10
  • Possibly reduces pain related to TMJ arthritis.10
  • May be able to reduce the need for total knee replacement surgery.9,10
  • 5 MTHF Activated may help to promote healthy levels of homo-cysteine, dopamine, and serotonin.11

Supplement Facts

Serving Size: 1 Capsule

Servings Per Container: 30

Folate (as 5-MTHFglucosamine salt)(Quatrefolic®)

5,000 mcg

Other Ingredients: Rice flour and hypromellose.

Dosage and Use:

  • As a dietary supplement, take one capsule per day or as directed by your healthcare professional. Dose may be repeated if necessary.

Research Links:


  • If pregnant, nursing, or undergoing treatment for a medical condition, consult your physician before taking this product
  • Keep out of reach of children
  • Do not exceed recommended dose


1. 5-Methyltetrahydrofolate Monograph. Alt Med Rev. 2006;11(4):330-37.
2. Abou-Saleh MT, Coppen A. Serum and red blood cell folate in depression. Acta Psychiatr Scand. 1989;80:78-82.
3. Cortese C, Motti C. MTHFR gene polymorphism, homocysteine and cardiovascular disease. Pub Health Nutr. 2001;4:493-97.
4. Doshi SN, McDowell IF, Moat SJ, et al. Folate improves endothelial function in coronary artery disease: an effect mediated by reduction of intracellular superoxide? Arterioscler Thromb Vasc Biol. 2001;21:1196-1202.
5. Halsted CH. The intestinal absorption of dietary folates in health and disease. J Am Coll Nutr. 1989;8;650-658. 6. Lambie DG, Johnson RH. Drugs and folate metabolism. Drugs. 1985;30:145-155.
7. Lamers Y, Prinz-Langenohl R, Bramswig S, Pietrzik K. Red blood cell folate concentrations increase more after supplementation with [6S]-5-methyltetrahydrofolate than with folic acid in women of childbearing age. Am J Clin Nutr. 2006;84:156-161.
8. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis.
9. Glucosamine
10. Glucosamine sulfate

* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.

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