Glutathione: The Master Antioxidant

We all need glutathione.

Considered to be the body’s most important self-generated antioxidants, glutathione (GSH) is also the most potent and most versatile. This vital nutrient is the natural antioxidant the body produces on its own. Age, disease and lifestyle can cause the body to stop making enough, and supplementing your body with glutathione becomes essential for maintaining your best health. Here at DR Vitamins, we know the importance of glutathione and want to help you build a glutathione pipeline which will in turn provide great health benefits. And not just for you, but for your friends and family as well. The more people who know about glutathione and what it does for the body, the more it can improve the health of society as a whole!

Dr. Mark Hyman says this about glutathione, “It is the most important molecule you need to stay healthy and prevent aging, cancer, heart disease, dementia and more, and necessary to treat everything from autism to Alzheimer’s disease. I called it the mother of all antioxidants.” There are a number of ways to increase the body’s glutathione absorption and development. Diet includes eating foods rich in glutathione and glutathione producing compounds, absorption involves utilizing the best ways of getting the highest amounts of glutathione in your system, and development is strengthening the body’s glutathione production methods.

Diet is the first step in promoting glutathione production, the following are great nutritious foods that help improve glutathione levels and overall health.

  • Sulfur rich foods like garlic and onions.
  • Cruciferous vegetables including broccoli, kale, collards, cabbage, cauliflower, and watercress.
  • Eggs and meat which contain good sources of sulfur.
  • Fresh fruit: Of the fruit family avocado is highest in sulfur content. Others rich in sulfur include kiwi, bananas, pineapple, strawberries, melons, grapefruit, grapes, oranges and peaches.
  • Other things we can eat to increase glutathione are grains, sesame seeds, cashews, peanuts, pistachios and other nuts.

 

Delivery. There are only two delivery systems that are effective in getting glutathione directly into our system. Foods and traditional supplements can help the body make its own glutathione, but due to problems with absorption and bioavailability there are no effective glutathione tablets or pills. Liposomal delivery and suppositories offer great absorption and are effective in boosting glutathione levels. Liposomal formulas are liquid supplements which are taken by mouth, the difference between them and swallow-able tablet supplements is that they are absorbed immediately into the body once in contact with the mouth thanks to phospholipids. Suppositories bypass the digestive system and allow the glutathione directly into the bloodstream, and can be absorbed in the highest amounts. We suggest glutathione suppositories from Vital Tox, Zetpil, and both Quicksilver Scientific and Results RNA offer the best quality liposomal methods.

Development. it is essential that we use good building blocks to help build our glutathione levels. Supplements that promote the production and retention of glutathione are just as important as good foods and glutathione itself in promoting your best health. Here are the top supplements that set up an internal environment where the body can produce and maintain the most glutathione.

  • N Acetyl Cysteine: A precursor to glutathione that helps your body make it. Life Extension sells a great NAC supplement that is both high quality and affordable.
  • Whey protein: A great source of cysteine and the amino acid building blocks for glutathione synthesis. Life Vitality has the one we recommend the highest, after all of our research and testing HydroSize by Life Vitality offers the highest absorption and is the easiest to digest. Using whey protein supplements can also improve muscle building and promote healthy weight.
  • Ascorbate C: A variety of the essential vitamin C, it helps you retain glutathione longer at the cellular level. This makes the glutathione the body produces last longer and capable of doing more good for the body before it needs to be replaced. We Pharmax for this, their Vital Mixed Ascorbates, with natural fruit antioxidants is easy to absorb, highly effective, improves immune system health, and the added fruit antioxidants can boost glutathione’s strength in protecting and healing the body.

Exercise can also improve glutathione levels, as well as overall health. 30 minutes of aerobic exercise at least 3 times a week and strength training exercises a few times a week are helpful and when combined with healthy diet, delivery, and development methods leads to great results.

If you’d like more information on methods of increasing your glutathione levels, or any of the products we recommend, we offer free consultations available to help you reach your health goals. Consultations are always free, with no pressure to buy, and we even have certified health consultants on staff to help provide our customers with the very best information to accomplish your goals.

There are many roles GSH play in our health including:

  • GSH is found in nearly every living cell in our bodies. Some of the highest concentrations are located in organs such as the liver, pancreas, spleen, kidneys, and the lens and cornea of the eye.
  • This very powerful antioxidant prevents the formation of free radicals and renders existing free radicals ineffective.
  • Aids in the production of white blood cells which affects our immune system. Therefore, GSH is one of the most potent anti-viral agents known.
  • Out of all the anti-cancer agents the body manufactures, GSH is the strongest.
  • Glutathione has the ability to return oxidized Vitamin C and Vitamin E back to their original unoxidized state.
  • The liver utilizes glutathione to detoxify acetaminophen, benzpyrene, formaldehyde, and many other toxins and carcinogens.
  • The brain requires GSH for normal, healthy function.
  • It maintains the congruity and purity of the red blood cells.
  • As we age, glutathione begins to diminish. By increasing GSH levels, the aging process can be slowed and cellular differentiation can take place.
  • Glutathione assists in creating nucleic acid and repairing DNA. It is also a required antioxidant to protect all our proteins.
  • GSH helps to maintain the redox potential of a cell.

GSH and Therapeutics

  • Detoxification
    • Heavy metal toxicity including mercury, lead, arsenic and cadmium
    • Common toxins that glutathione may help protect against are car exhaust, cigarette smoke, aspirin and alcohol (Marz, p. 78, 1997)
    • Pesticide and industrial chemical exposure
    • Steroids
    • Bacterial toxins (Clostridia difficile)
    • Pharmaceuticals (very long list that need to be detoxified by the liver) (Marz, p. 79, 1997)
  • Immune enhancement: 1-3 grams per day. This is especially effective against clostridium in the GI. It helps prevent translocation.
  • Psoriasis
  • Diabetes mellitus: Especially in ketosis as DM patients will generally excrete increased amounts of sulfur containing amino acids.
  • Liver disease including cirrhosis and fatty liver disease caused by alcohol: Studies show mild effects at large doses.
  • Ulcers intestinal or stomach: In patients with stomach ulcers low levels of GSH have been found.
  • Aspirin or phenacetin overdose (useful for rheumatoid arthritis patients or chronic pain sufferers on 8 or more aspirin/day).
  • Hematological conditions: myelofibrosis, acute leukemia, chronic myelocytic leukemia, lymphoma, polycythemia vera.
  • Alcoholism.
  • Before ionizing radiation therapy.
  • Cataracts.
  • Parkinson’s disease, Alzheimers, ALS, MS and other neurologic conditions including Autism/Pervasive Developmental Delay.
  • Chronic kidney failure.

GSH and Metabolism

  • Glutathione is synthesized in the body from 3 amino acids: Cysteine, glutamine and glycine. Cysteine is one of the sulfur containing amino acids used for the synthesis of glutathione, which is very critical in detoxification. N Acetyl Cysteine (NAC) is the rate limiting amino acid for the production of glutathione within the cells of the body, has mucolytic properties, and is a powerful antioxidant and detoxifier. Some research indicates that NAC is more readily absorbed into certain cells of the body than glutathione and is therefore an excellent synergist with glutathione. The thiol group is the active part of the molecule which serves as a reducing agent to prevent oxidation of tissues.
  • Reduced Glutathione: Glutathione acts as one of the major detoxifiers in the body, but it must be in the reduced form to work properly. Sometimes glutathione will be listed on the label of a product, however it wont be specifically listed as being reduced. The unreduced form is much cheaper and isn’t metabolically active. Riboflavin, niacinamide, selenium, lipoic acid and glutathione reductase are all essential cofactors for generating reduced glutathione. Once the cysteine moieties become oxidized, they combine to form cystine. Cystine taken by itself is poorly absorbed.
  • Glutathione peroxidase is another compound which is involved in detoxification against peroxides and other xenobiotics. It is synthesized from selenium and cysteine.
  • There are no known toxicity issues or contraindications.

Thank you for taking the time to read Glutathione: The Master Antioxidant.

Your success is our passion. If you have any questions or contributions, please contact us via email or phone-call. We are constantly looking for new information to promote wellness – and hearing from you would make our day! Feel free to reach out to our free Health and Wellness Consultation headed by our Certified Health Consultant, Kurt LaCapruccia, D.S.S. (Diploma in Dietary Supplement Science).

Live Vibrantly! – DR Vitamin Solutions

P.S.- At the end of the day, we are health-nerds here at DR Vitamin Solutions. We recommend you discover our Vital Tox Glutathione Suppository as your all-in-one supplement to boost your Glutathione levels! Or browse the DR Vitamin Glutathione Store for all your Glutatione needs.